• Yuqing Gu and Zhuyin Qian.
• Pancreas Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.
• Medicine (Baltimore). 2018 Jun 1; 97 (22): e10911.

RationalePancreatic pseudocyst can present single or multiple, inside or outside the pancreas. Pancreatic panniculitis is a rare skin lesion in pancreatic disease patients. The purpose of this study is to report a case of chronic pancreatitis coexisting with multiple pseudocysts and pancreatic panniculitis.Patient ConcernsA 46-year-old man with chronic pancreatitis presented multiple small cystic lesions inside the head of the pancreas and two large cystic lesions adjacent to the tail of the pancreas. The patient also developed subcutaneous nodules involving upper and lower limbs, hands, and lower abdomen bilaterally.DiagnosisThe patient was diagnosed with pancreatic pseudocyst and pancreatic panniculitis resulted from chronic pancreatitis.InterventionsBile duct stent and pancreatic duct stent placement was performed endoscopicly.OutcomesPanniculitis faded three weeks later and the pancreatic pseudocysts disappeared six weeks later.LessonsClinicians should be aware of the manifestation of multiple pancreatic pseudocyst and pancreatic panniculitis, and endoscopic transpapillary drainage may be a effective way in this scenario.

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