• Lei Shi, Yuanshun Zhao, and Wen Li.
• Department of Endoscopy, Tianjin Union Medical Center, 190, Jieyuan Road, Hongqiao District, Tianjin, China.
• Medicine (Baltimore). 2018 Jun 1; 97 (23): e10995e10995.

RationaleColonic lipomas are uncommon benign submucosal adipose tumorsthat are usually asymptomatic. Large lipomas can cause symptoms require treatment in principle. We report 1 case of giant colonic lipoma removed with endoloop-assisted unroofing technique instead of conventional surgical bowel resection.Patient ConcernsA 62-year-old female patient presented with intermittent abdominal discomfort for 1 month.DiagnosisThe patient was diagnosed as having a giant colonic lipoma.InterventionEndoscopic resection with endoloop-assisted unroofing technique was performed. On the 22nd day after resection, intestinal obstruction occurred by shedding mass was found; the symptoms of this patient disappeared soon after removal of the mass by endoscopy.OutcomesA follow-up colonoscopy 6 months later showed a scarred mucosa at the ligation site and no residual lipoma was observed.LessonsEndoscopic resection with endoloop-assisted unroofing technique remains a viable option for giant lipomas; however, postoperative intestinal obstruction caused by shedding mass should be noted.

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