• Hyeok Dong Lee, Sung Young Lee, Young-Shin Cho, Seung Hoon Han, Si-Bog Park, and Kyu Hoon Lee.
• Department of Rehabilitation Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
• Medicine (Baltimore). 2018 Jun 1; 97 (23): e11051.

RationalePeripheral neuropathy is a rare complication of carbon monoxide intoxication. Peripheral neuropathy following carbon monoxide intoxication is known to completely recover within a few months.Patient ConcernsA 40-year-old man complained of motor weakness and hypoesthesia of the right lower extremity with swelling of his right thigh after carbon monoxide intoxication resulting from a suicide attempt.DiagnosesFollowing nerve conduction and electromyographic studies, the patient was diagnosed with sciatic neuropathy with severe axonopathy. Clinical and laboratory findings led to a diagnosis of rhabdomyolysis.InterventionsThe patient was treated conservatively for rhabdomyolysis and underwent comprehensive rehabilitation for sciatic neuropathy during hospitalization.OutcomesAfter discharge, he underwent serial follow-up tests with nerve conduction and electromyographic studies, which showed prolonged persistence of sciatic neuropathy; however, he showed significant improvement at his 26-month post-discharge follow-up.LessonPatients presenting with peripheral neuropathy secondary to carbon monoxide intoxication may show variable recovery periods; however, a favorable prognosis can be expected regardless of the concomitant occurrence of rhabdomyolysis and/or compartment syndrome.

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