• Lingxing Wang, Shanyan Hong, Honghong Huang, and Meili Yang.
• Department of Neurology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
• Medicine (Baltimore). 2018 Jun 1; 97 (26): e11281.

RationaleRhabdomyolysis owing to status epilepticus (SE) can be life-threating, with acute kidney injury (AKI) the most serious complication; therefore, early recognition of the risk factors is important. Hyperuricemia after epileptic seizures has been reported, and severe hyperuricemia can lead to acute renal function damage.Patient ConcernsWe present the case of a 21-year-old man hospitalized for SE, who had especially high level of blood uric acid (UA) at initial presentation.DiagnosisThe patient was diagnosed with rhabdomyolysis due to SE.InterventionsThe patient was treated with hydration and bicarbonate therapy. But he developed acute kidney failure (AKF) and hemodialysis was performed.OutcomesAfter hemodialysis, his symptoms disappeared and laboratory data returned to normal.LessonsHyperuricemia after SE might indicate severe muscle damage or reduced clearance of metabolites, and could be a risk factor for kidney dysfunction, especially with rhabdomyolysis. To our knowledge, this is the first report of rhabdomyolysis following SE with hyperuricemia.

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