• Curr Opin Neurol Neurosurg · Apr 1992

    Review

    Pain mechanisms and the management of neuropathic pain.

    • J Alexander and A Black.
    • Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary, UK.
    • Curr Opin Neurol Neurosurg. 1992 Apr 1;5(2):228-34.

    AbstractThe nociceptive system is not fixed, but changes in response to its input and activity. This 'plasticity' comprises dynamic developments of both pro- and antinociceptive processes. Recent advances in the understanding of these processes have important implications for the treatment of persistent neuropathic pain.

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