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- Masakazu Nakamura, Shigehisa Ura, Ichiro Yabe, Mika Otsuki, Hiroyuki Soma, and Akihiko Ogata.
- Department of Neurology, Hokkaido Neurosurgical Memorial Hospital, Japan.
- Intern. Med. 2022 Oct 15; 61 (20): 311531203115-3120.
AbstractCat scratch disease (CSD) is a zoonotic infection caused by Bartonella henselae typically resulting in self-limited regional lymphadenopathy. Encephalitis is a complication with a supposedly benign prognosis, but we encountered an exceptional case. A 19-year-old Japanese woman presented with status epilepticus. She was diagnosed with CSD-associated encephalitis based on her history of contact with a kitten and a high titre of serum IgG to B. henselae. Multimodal treatment ameliorated her encephalitis, but neurological sequelae including spastic paraparesis, persisted. After several months, she developed age-disproportionate parkinsonism inconsistent with a neurodegenerative disease. In conclusion, CSD-associated encephalitis can result in severe neurological sequelae and post-encephalitic parkinsonism.
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