• Internal medicine journal · Mar 2022

    Review Case Reports

    Rapidly progressive crescentic diabetic nephropathy: two case reports.

    • Jade E Schroers, Alexander M Gilbert, Paul R McKenzie, Paul D Kirwan, Steven J Chadban, and Tracey Ying.
    • Kidney Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
    • Intern Med J. 2022 Mar 1; 52 (3): 479-484.

    AbstractCrescents are not a well recognised feature of diabetic nephropathy. We present two cases of patients presenting with a rapid decline in renal function and subacute onset of nephrotic syndrome. Glomerulonephritis screening was negative, and renal biopsy revealed non-necrotising cellular crescents and typical features of late-stage diabetic nephropathy. We review the literature for diabetic nephropathy with crescents and explore possible underlying mechanisms.© 2022 Royal Australasian College of Physicians.

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