• Neuromodulation · Jan 2016

    Electrical Stimulation Able to Trigger Locomotor Spinal Circuits Also Induces Dorsal Horn Activity.

    • Nejada Dingu, Ronald Deumens, and Giuliano Taccola.
    • Neuroscience Department, International School for Advanced Studies (SISSA), Trieste, Italy.
    • Neuromodulation. 2016 Jan 1; 19 (1): 38-46.

    ObjectivesInvestigate whether electrical stimulation of the spinal cord adapted to trigger locomotor patterns additionally influences dorsal horn networks.Materials And MethodsAn in vitro model of isolated neonatal rat spinal cord was used to repetitively deliver electrical stimuli to lumbar dorsal roots and record from homolateral lumbar dorsal roots and ventral roots.ResultsRepetitive electrical lumbar dorsal root stimulation can affect both locomotor rhythms derived from ventral neuronal circuits and activity from dorsal neuronal circuits.ConclusionThese data suggest that neuro-electrostimulation protocols can simultaneously activate functionally distinct spinal neuronal circuits.© 2015 International Neuromodulation Society.

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