• Haitao Jia, Yanhong Xing, Shuangyin Zhang, and Yingbin Wang.
• Department of Anesthesiology, Lanzhou University Second Hospital, Lanzhou, China.
• Medicine (Baltimore). 2018 Sep 1; 97 (39): e12543.

RationaleMyxoma is the most common primary benign cardiac tumor, which could lead to some fatal complications because of its strategic position.Patient ConcernsThe patient was admitted to our hospital due to sudden onset of palpitation, chest tightness, mild fever, night sweats, accompanied with bilateral lower extremities adynamia, and paralysis for 5 days, but no obvious syncope and edema.DiagnosesTransthoracic echocardiography showed a giant mobile myxoma (72 × 58 mm) in the right atrium (RA). Magnetic resonance imaging revealed an erosive space-occupying lesion located between the first and third thoracic vertebrae.InterventionsThoracic vertebral lesions were resected immediately to rescue the incomplete paraplegia. After the patient was placed in the prone position, significant hemodynamics changes were observed due to the displacement of the huge RA myxoma.OutcomesStable hemodynamics was maintained during the operation through control of fluid infusion combined with vasoactive drugs.LessonsChange in body position may lead to obstruction of intracardiac blood flow in patients with giant myxoma. This clinical manifestation is rarely reported.

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