• C Francoeur, W P Landis, M Winters, M Y Naim, A Donoghue, C L Dominick, J W Huh, J M MacDonald, S S Lang, I Yuan, R A Berg, V M Nadkarni, T J Kilbaugh, R M Sutton, M P Kirschen, R W Morgan, and A A Topjian.
• Department of Pediatrics, CHU de Québec - Université Laval Research Center, Quebec, Canada. Electronic address: conall.francoeur.med@ssss.gouv.qc.ca.
• Resuscitation. 2022 May 1; 174: 354135-41.

AimCerebral oxygenation (rSO2) is not routinely measured during pediatric cardiopulmonary resuscitation (CPR). We aimed to determine whether higher intra-arrest rSO2 was associated with return of spontaneous circulation (ROSC) and survival to hospital discharge.MethodsProspective, single-center observational study of cerebral oximetry using near-infrared spectroscopy (NIRS) during pediatric cardiac arrest from 2016 to 2020. Eligible patients had ≥30 s of rSO2 data recorded during CPR. We compared median rSO2 and percentage of rSO2 measurements above a priori thresholds for the entire event and the final five minutes of the CPR event between patients with and without ROSC and survival to discharge.ResultsTwenty-one patients with 23 CPR events were analyzed. ROSC was achieved in 17/23 (73.9%) events and five/21 (23.8%) patients survived to discharge. The median rSO2 was higher for events with ROSC vs. no ROSC for the overall event (62% [56%, 70%] vs. 45% [35%, 51%], p = 0.025) and for the final 5 minutes of the event (66% [55%, 72%] vs. 43% [35%, 44%], p = 0.01). Patients with ROSC had a higher percentage of measurements above 50% during the final five minutes of CPR (100% [100%, 100%] vs. 0% [0%, 29%], p = 0.01). There was no association between rSO2 and survival to discharge.ConclusionsHigher cerebral rSO2 during CPR for pediatric cardiac arrest was associated with higher rates of ROSC but not with survival to discharge.Copyright © 2022 Elsevier B.V. All rights reserved.

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