• Br J Anaesth · Jul 2022

    Editorial

    Avoiding kidney damage in ICU sedation with sevoflurane: use isoflurane instead.

    • J Robert Sneyd.
    • Faculty of Medicine and Dentistry, University of Plymouth, Plymouth, UK. Electronic address: robert.sneyd@pms.ac.uk.
    • Br J Anaesth. 2022 Jul 1; 129 (1): 7-10.

    AbstractIntensive care unit (ICU) sedation with sevoflurane is associated with nephrogenic diabetes insipidus. Given that isoflurane is now licenced (in Europe) for ICU sedation and has Investigational New Drug status in the USA, evidence indicates that clinicians should stop using sevoflurane in this indication except in the context of clinical trials.Copyright © 2022 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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