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- Makiko Nakamura, Teruhiko Imamura, Takuya Fukui, Naoya Kataoka, and Koichiro Kinugawa.
- The Second Department of Internal Medicine, University of Toyama, Japan.
- Intern. Med. 2022 Oct 15; 61 (20): 306330673063-3067.
AbstractPatients with arrhythmogenic right ventricular cardiomyopathy (ARVC) classically present with ventricular arrhythmias and less commonly heart failure. ARVC is an inherited cardiomyopathy and generally based on a variant of desmosomal genes. Recently, the association between myocardial inflammation and ARVC has been a matter of great concern. We encountered a patient with ARVC who had a desmoglein-2 mutation with advanced right ventricular failure accompanying a preserved left ventricular function. Concomitant right ventricular myocarditis was detected four years after the diagnosis of ARVC. ARVC and myocarditis might have a deep pathophysiological association, at least in some cases.
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