• Internal medicine · Jun 2022

    Case Reports

    Polymyalgia Rheumatica Following COVID-19 Vaccination: A Case Report.

    • Akira Yokote, Shinsuke Fujioka, Nobutaka Takahashi, Takayasu Mishima, and Yoshio Tsuboi.
    • Department of Neurology, Fukuoka University School of Medicine, Japan.
    • Intern. Med. 2022 Jun 1; 61 (11): 177517771775-1777.

    AbstractWe herein report a 71-year-old woman presented with a fever, arthralgia, general malaise and leg muscle stiffness following administration of the COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). Laboratory findings showed an elevated C-reactive protein level and erythrocyte sedimentation rate. In addition, Gallium-67 scintigraphy demonstrated an increased uptake in multiple joints. Typing of human leukocyte antigen (HLA) revealed the presence of the DRB1*0404/*0803 allele. These findings met the diagnostic criteria for polymyalgia rheumatica (PMR), and when we started steroid treatment, her symptoms improved rapidly. This patient developed PMR after receiving a COVID-19 mRNA vaccine (Comirnaty, Pfizer-BioNTech). This case is considered to be valuable, as the HLA-DRB1 allele was also confirmed.

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