• Internal medicine · Jun 2022

    Case Reports

    Sensory Ataxic Guillain-Barré Syndrome with Dysgeusia after mRNA COVID-19 Vaccination.

    • Shunsuke Ogata, Yoshito Ishii, Keiichiro Asano, Erena Kobayashi, Shun Kubota, Keita Takahashi, Yosuke Miyaji, Yuichi Higashiyama, Hideto Joki, Hiroshi Doi, Michiaki Koga, Hideyuki Takeuchi, and Fumiaki Tanaka.
    • Department of Neurology and Stroke Medicine, Yokohama City University Graduate School of Medicine, Japan.
    • Intern. Med. 2022 Jun 1; 61 (11): 1757-1760.

    AbstractGuillain-Barré syndrome (GBS) has occasionally occurred in people who have received coronavirus disease 2019 (COVID-19) vaccines. Dysgeusia is rare symptom of GBS. We herein report a rare case of sensory ataxic GBS with dysgeusia just after the second dose of the Pfizer-BioNTech COVID-19 vaccine. Although autoantibodies against glycolipids were not detected, immunotherapy with intravenous immunoglobulin and methylprednisolone pulse therapy effectively ameliorated the symptoms. Our report suggests that the COVID-19 vaccine may induce various clinical subtypes of GBS, including a rare variant with sensory ataxia and dysgeusia.

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