• D Moher, A Tsertsvadze, A C Tricco, M Eccles, J Grimshaw, M Sampson, and N Barrowman.
• Chalmers Research Group, Children's Hospital of Eastern Ontario, 401 Smyth Road, Room R226, Ottawa, Ontario, Canada, K1H 8L1. dmoher@uottawa.ca
• Cochrane Db Syst Rev. 2008 Jan 23; 2008 (1): MR000023MR000023.

BackgroundSystematic reviews are most helpful if they are up-to-date. We did a systematic review of strategies and methods describing when and how to update systematic reviews.ObjectivesTo identify, describe and assess strategies and methods addressing: 1) when to update systematic reviews and 2) how to update systematic reviews.Search StrategyWe searched MEDLINE (1966 to December 2005), PsycINFO, the Cochrane Methodology Register (Issue 1, 2006), and hand searched the 2005 Cochrane Colloquium proceedings.Selection CriteriaWe included methodology reports, updated systematic reviews, commentaries, editorials, or other short reports describing the development, use, or comparison of strategies and methods for determining the need for updating or updating systematic reviews in healthcare.Data Collection And AnalysisWe abstracted information from each included report using a 15-item questionnaire. The strategies and methods for updating systematic reviews were assessed and compared descriptively with respect to their usefulness, comprehensiveness, advantages, and disadvantages.Main ResultsFour updating strategies, one technique, and two statistical methods were identified. Three strategies addressed steps for updating and one strategy presented a model for assessing the need to update. One technique discussed the use of the "entry date" field in bibliographic searching. Statistical methods were cumulative meta-analysis and predicting when meta-analyses are outdated.Authors' ConclusionsLittle research has been conducted on when and how to update systematic reviews and the feasibility and efficiency of the identified approaches is uncertain. These shortcomings should be addressed in future research.

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