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- Luara L Arana-Luna, Martha Alvarado-Ibarra, Luis G Silva-Michel, Adrián Morales-Maravilla, María Del C González-Rubio, Lénica A Chávez-Aguilar, Ma Fernanda Tena-Iturralde, Liliana Mojica-Balceras, Nidia Zapata-Canto, Patricia Galindo-Delgado, Ma Raquel Miranda-Madrazo, Alba E Morales-Hernández, Karina Silva-Vera, Flavio A Grimaldo-Gómez, Álvaro Hernández-Caballero, Ramón A Bates-Martin, José L Álvarez-Vera, Fredy Tepepa-Flores, Óscar Teomitzi-Sánchez, Denisse J Fermín-Caminero, Peña-CelayaJosé A de laJAServicio de Hematología, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico., Óscar Salazar-Ramírez, Luz V Flores-Villegas, Lidia V Guerra-Alarcón, Faustino Leyto-Cruz, Sergio I Inclán-Alarcón, Andrea I Milán-Salvatierra, Yanet Ventura-Enríquez, Uendy Pérez-Lozano, Pamela E Báez-Islas, Ana L Tapia-Enríquez, Orlando G Palma-Moreno, Jocelyn Aguilar-Luévano, Arturo Espinosa-Partida, Luis F Pérez-Jacobo, Flavio Rojas-Castillejos, Josué I Ruiz-Contreras, Sergio J Loera-Fragoso, Jesús E Medina-Coral, Brenda L Acosta-Maldonado, Emely J Soriano-Mercedes, Erick E Saucedo-Montes, Luis M Valero-Saldana, Susana G González-Prieto, Lorena Nava-Villegas, Ana K Hernández-Colin, Areli E Hernández-Alcántara, Pedro A Zárate-Rodríguez, Gregorio Ignacio-Ibarra, Luis A Meillón-García, Karla A Espinosa-Bautista, Cindy Ledesma-de la Cruz, Diego M Barbosa-Loría, Carolina García-Castillo, Carolina Balderas-Delgado, Álvaro Cabrera-García, Juan M Pérez-Zúñiga, Eleazar Hernández-Ruiz, Atenas Villela-Peña, Sue Cynthia Gómez Cortés, Hilda Romero-Rodelo, Katheryn B Garzón-Velásquez, Cristina Serrano-Hernández, Annel Martínez-Ríos, Ma Luisa Pedraza-Solís, Jorge A Martínez-Coronel, Iris M Narváez-Davalos, Alinka S García-Camacho, Laura E Merino-Pasaye, Carolina Aguilar-Andrade, Juan A Aguirre-Domínguez, Pedro G Guzmán-Mera, Elizabeth Delgado-de la Rosa, Perla E Flores López, Lilia L González-Aguirre, Edgar M Ramírez-Alfaro, Heidi Vera-Calderón, Ma Lizeth Meza-Dávalos, Juan Murillo-Cruz, Yayra M Pichardo-Cepín, and Eva F Ramírez-Romero.
- Servicio de Hematología, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
- Gac Med Mex. 2022 Jan 1; 158 (M3): M1-M48.
AbstractAcute myeloid leukemia (AML) comprises a heterogeneous group of hematopoietic cell neoplasms of myeloid lineage that arise from the clonal expansion of their precursors in the bone marrow, interfering with cell differentiation, leading to a syndrome of bone marrow failure. AML is a consequence of genetic and epigenetic changes (point mutations, gene rearrangements, deletions, amplifications, and arrangements in epigenetic changes that influence gene expression) in hematopoietic precursor cells, which create a clone of abnormal cells that are capable of proliferating but cannot differentiate into mature hematopoietic cells or undergo programmed cell death. The diagnosis requires more than 20% myeloid blasts in the bone marrow and certain cytogenic abnormalities. Treatment will depend on age, comorbidities, and cytogenetic risk among the most frequent.Copyright: © 2022 Permanyer.
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