• World Neurosurg · Sep 2018

    Review

    Diagnosis, Therapy, and Therapeutic Effects in Cases of Pituitary Metastasis.

    • Yi Zhao, Wei Lian, Bing Xing, Ming Feng, Xiaohai Liu, Renzhi Wang, and Weixun Zhou.
    • Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
    • World Neurosurg. 2018 Sep 1; 117: 122-128.

    ObjectiveThis study aimed to summarize the diagnosis, therapy, and prognosis of pituitary metastasis.MethodsTen patients from the Department of Neurosurgery of the Peking Union Medical College Hospital from April 1997 to August 2014 were retrospectively analyzed.ResultsThe participants included 7 males (70%) and 3 females (30%), with an average age of 60.4 years. The most common initial clinical feature was visual disability (50%). The postoperative pathology reports indicated 1 case (10%) of metastatic large-cell pulmonary carcinoma, 2 cases (20%) of metastatic small cell pulmonary carcinoma, 2 cases (20%) of clear cell renal carcinoma metastasis, and 5 cases (50%) of metastasis of adenocarcinomas from different areas. All the patients underwent a thorough follow-up, and the average survival was 144 days.ConclusionsPituitary metastasis is a rare disease. Its diagnosis depends on the clinical manifestations and radiologic results. The primary therapeutic method is surgery and subsequent radiotherapy and chemotherapy; however, the prognosis of this disease is poor.Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

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