• Serpil Erdoğan, Ozhan Ozdemir, Halef Okan Doğan, Sevilay Sezer, Cemal Reşat Atalay, Fatma Meriç, Fatma Meriç Yilmaz, and Yüksel Koca.
• Department of Biochemistry, Ankara Numune Training and Research Hospital, Turkey.
• Turk J Med Sci. 2014 Jan 1; 44 (1): 121-5.

AimTo investigate the value of measuring liver enzymes, red cell distribution width (RDW), and mean platelet volume (MPV) in predicting the development of gestational diabetes mellitus (GDM).Materials And MethodsThe medical records of all pregnant women followed by the obstetrics clinic between January 2010 and November 2012 were systematically evaluated, and patients with a diagnosis of GDM were identified. A total of 68 patients with GDM and 61 healthy controls were included in the study. Results of relevant laboratory parameters were recorded.ResultsOut of all the parameters evaluated, mean values for platelet distribution width (PDW) and mean activities of alanine transaminase (ALT) and gamma-glutamyl transferase (GGT) were significantly higher in the GDM group compared to healthy controls (P = 0.003, P = 0.015, and P = 0.021, respectively), whereas mean plateletcrit (PCT) levels were significantly lower in the GDM group (P = 0.002). No significant difference was observed between groups in terms of MPV, RDW, platelet count, and aspartate transaminase levels.ConclusionOur study results suggest that ALT, GGT, PCT, and PDW may be useful as predictors of impending GDM.

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