• Kelli D Allen, William S Yancy, Hayden B Bosworth, Cynthia J Coffman, Amy S Jeffreys, Santanu K Datta, Jennifer McDuffie, Jennifer L Strauss, and Eugene Z Oddone.
• Ann. Intern. Med. 2016 Jan 19; 164 (2): 73-83.

BackgroundManagement of osteoarthritis requires both medical and behavioral strategies, but some recommended therapies are underused.ObjectiveTo examine the effectiveness of a combined patient and provider intervention for improving osteoarthritis outcomes.DesignCluster randomized clinical trial with assignment to osteoarthritis intervention and usual care groups. (ClinicalTrials.gov: NCT01130740).SettingDepartment of Veterans Affairs Medical Center in Durham, North Carolina.Participants30 providers (clusters) and 300 outpatients with symptomatic hip or knee osteoarthritis.InterventionThe telephone-based patient intervention focused on weight management, physical activity, and cognitive behavioral pain management. The provider intervention involved delivery of patient-specific osteoarthritis treatment recommendations to primary care providers through the electronic medical record.MeasurementsThe primary outcome was total score on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at 12 months. Secondary outcomes were WOMAC function and pain subscale scores, physical performance (Short Physical Performance Battery), and depressive symptoms (Patient Health Questionnaire-8). Linear mixed models that were adjusted for clustering of providers assessed between-group differences in improvement in outcomes.ResultsAt 12 months, WOMAC scores were 4.1 points lower (indicating improvement) in the osteoarthritis intervention group versus usual care (95% CI, -7.2 to -1.1 points; P = 0.009). WOMAC function subscale scores were 3.3 points lower in the intervention group (CI, -5.7 to -1.0 points; P = 0.005). WOMAC pain subscale scores (P = 0.126), physical performance, and depressive symptoms did not differ between groups. Although more patients in the osteoarthritis intervention group received provider referral for recommended osteoarthritis treatments, the numbers who received them did not differ.LimitationThe study was conducted in a single Veterans Affairs medical center.ConclusionThe combined patient and provider intervention resulted in modest improvement in self-reported physical function in patients with hip and knee osteoarthritis.Primary Funding SourceDepartment of Veterans Affairs, Health Services Research and Development Service.

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