• Turk J Med Sci · Jan 2015

    Cardiac factors affecting the success of vardenafil in erectile dysfunction.

    • Kürşad Zengin, Hüseyin Ede, Serhat Tanik, Sebahattin Albayrak, Savaş Sarikaya, Aliriza Erbay, Muhammet Abdurrahim Imamoğlu, and Mesut Gürdal.
    • Turk J Med Sci. 2015 Jan 1; 45 (4): 751-7.

    Background/AimTo evaluate the predictability of vardenafil success in patients with erectile dysfunction (ED) by using cardiological tests.Materials And MethodsPatients diagnosed with ED who did not benefit from lifestyle changes (n = 68) were evaluated with an abridged 5-item version of the International Index of Erectile Function (IIEF-5). The pretreatment and posttreatment IIEF-5 scores were compared with pretreatment data obtained from cardiological examinations.ResultsWhen pretreatment scores were compared with test parameters, mitral flow E/A ratio and tissue Doppler imaging (TDI) E'/ A', exercise test duration, exercise capacity in MET, and percentage of maximum heart rate were found to be statistically significant. Furthermore, there was a significant negative correlation between mitral flow E/A ratio, TDI E'/A', exercise test duration, exercise capacity in MET, and the difference in post- and pretreatment IIEF-5 scores.ConclusionAs a diastolic function indicator, TDI E'/A' positively correlates with pretreatment IIEF-5 scores and negatively correlates with the beneficial effect of vardenafil treatment. As a result, the cardiological status of the patient correlates with individual IIEF-5 scores, and it seems to be useful in predicting vardenafil success.

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