• J Chin Med Assoc · Feb 2018

    Randomized Controlled Trial Comparative Study

    Clinical course in infants diagnosed with transient tachypnea of newborn: A clinical trial assessing the role of conservative versus conventional management.

    • M Dehdashtian, M Aletayeb, A Malakian, M R Aramesh, and H Malvandi.
    • Imam Khomeini Hospital, Department of Pediatrics, Neonatal Intensive Care Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: dehdashtian@ajums.ac.ir.
    • J Chin Med Assoc. 2018 Feb 1; 81 (2): 183-186.

    BackgroundTransient tachypnea of the newborn (TTN) is a respiratory disorder secondary to inadequate or delayed clearance of lung fluids. Early symptoms of the disease are indistinguishable from neonatal respiratory distress syndrome, pneumonia, and persistent pulmonary hypertension. Therefore, these newborns, in addition to receiving conservative management, receive antibiotics until blood cultures provide definite results. In this study, we assessed the clinical course of neonates diagnosed with TTN who received conventional versus conservative management.MethodsOne hundred and thirty neonates diagnosed as having TTN were randomly enrolled in two study groups. While patients belonging to one group received conservative management, those from the other group were treated with conventional medical therapy.ResultsMean duration of hospitalization was 7 ± 0.2 in the conventional and 5 ± 1.5 in the conservative group. Duration of antibiotic therapy was 6.7 ± 2.47 days in the conventional group.ConclusionNewborns diagnosed with TTN without prenatal risk factors and a negative C reactive protein test do not need to be administered antibiotics and hospitalized until confirmatory blood culture results are obtained.Copyright © 2017. Published by Elsevier Taiwan LLC.

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