• Int. J. Clin. Pract. · Sep 2012

    Meta Analysis Comparative Study

    Structured management strategy based on the Gastro-oesophageal Reflux Disease (GERD) Questionnaire (GerdQ) vs. usual primary care for GERD: pooled analysis of five cluster-randomised European studies.

    • J Ponce, V Garrigues, L Agréus, E Tabaglio, M Gschwantler, E Guallar, M Tafalla, J Nuevo, and J Hatlebakk.
    • Digestive Functional Disorders Unit, Hospital Universitario La Fe, Valencia, Spain. jponceg@medynet.com
    • Int. J. Clin. Pract. 2012 Sep 1; 66 (9): 897905897-905.

    BackgroundResponse to treatment among primary care patients with gastro-oesophageal disease (GERD) is variable.AimThe GERD Management Project (GMP) evaluated the effectiveness of a structured management approach to GERD vs. standard treatment (usual care).MethodsData from five cluster-randomised clinical trials in adult primary care patients with symptoms of GERD were pooled. The structured pathway was based on the self-administered GERD Questionnaire (GerdQ) and was compared with standard treatment.Results1734 patients were enrolled (structured treatment, n=834; standard treatment, n=900). The difference in the mean GerdQ score change from baseline favoured the structured pathway (-0.61; 95% CI: -0.88, -0.34; p<0.001). The odds ratio for an indication for treatment revision at the end of follow-up (structured vs. standard treatment) was 0.39 (95% CI: 0.29, 0.52; p=0.001).ConclusionsManagement of primary care patients with GERD can be improved by systematic stratification of patients using a patient management tool such as the GerdQ.© 2012 Blackwell Publishing Ltd.

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