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- Hyun-Jin Choi, Ji-Soo Baek, Cheon-Hoo Jeon, Seon-Mi Shin, and Chung-Sik Cho.
- College of Korean Medicine, Daejeon University, Daejeon, Republic of Korea.
- Medicine (Baltimore). 2022 Mar 25; 101 (12): e29079e29079.
BackgroundThe purpose of a systematic review and meta-analysis is to verify the clinical efficacy and safety of Geumguesingihwan for patients with uncomplicated type 2 diabetes.MethodsThe systematic review and meta-analysis will be performed following the guidelines of the National Evidence-based Healthcare Collaborating Agency. We will conduct a systematic search of randomized controlled trials in 8 electronic databases until August 31, 2021.ResultsThis study will provide evidence regarding the clinical efficacy of Geumguesingi-hwan from the following 3 perspectives: improving blood glucose level, insulin resistance, and β-cell function. Additionally, we will examine the safety of Geumguesingi-hwan by evaluating the adverse effects.ConclusionsThis study will verify the antidiabetic efficacy and safety of Geumguesingi-hwan in patients with uncomplicated type 2 diabetes.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
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