• Yue Yuan, Ying Gao, Zihui Ding, Ying Qiao, Sanpeng Xu, Zhe Tang, Ying Liao, and Ping Li.
• School of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.
• Medicine (Baltimore). 2022 Feb 18; 101 (7): e28843e28843.

BackgroundConstipation is one of the common problems in stroke patients, which seriously affects the life quality of patients and even leads to the recurrence of cerebrovascular disease. The clinical trials of acupoint herbal patching (AHP) in the adjuvant treatment of constipation after stroke (CAS) is currently in progress. However, there is no systematic review or meta-analysis to evaluate the effects of AHP on CAS.MethodsWe will search articles in 8 electronic databases including the Cochrane Central Register of Controlled Trials, PubMed, Embase, the Web of Science, China National Knowledge Infrastructure, the Chinese Biomedical Literature Database, Wanfang Database, and the Chinese Scientific Journal Database for randomized controlled trials of CAS treated by AHP from their inception to November 1, 2021. The primary outcome measures will be clinical effective rate, defecation frequency, improvement of clinical symptoms including complete spontaneous bowel movements. The data meeting the inclusion criteria were analyzed by RevMan V.5.4 software. Two authors evaluated the study using the Cochrane collaborative risk bias tool. We will use a scoring method to assess the overall quality of evidence supporting the main results.ResultsThis study will analyze the clinical effective rate, defecation frequency, improvement of clinical symptoms including complete spontaneous bowel movements after stroke.ConclusionThe findings of this systematic review will provide evidence to evaluate the effectiveness and safety of AHP for CAS.Inplasy Registration NumberINPLASY202210065.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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