• Kishore L Jayakumar, Julia A Lavenberg, Matthew D Mitchell, Jalpa A Doshi, Brian Leas, David R Goldmann, Kendal Williams, Patrick J Brennan, and Craig A Umscheid.
• University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
• J Hosp Med. 2016 Mar 1; 11 (3): 185-92.

BackgroundHospital evidence-based practice centers (EPCs) synthesize and disseminate evidence locally, but their impact on institutional decision making is unclear.ObjectiveTo assess the evidence synthesis activities and impact of a hospital EPC serving a large academic healthcare system.Design, Setting, And ParticipantsDescriptive analysis of the EPC's database of rapid systematic reviews since EPC inception (July 2006-June 2014), and survey of report requestors from the EPC's last 4 fiscal years.MeasurementsDescriptive analyses examined requestor and report characteristics; questionnaire examined report usability, impact, and requestor satisfaction (higher scores on 5-point Likert scales reflected greater agreement).ResultsThe EPC completed 249 evidence reviews since inception. The most common requestors were clinical departments (29%, n = 72), chief medical officers (19%, n = 47), and purchasing committees (14%, n = 35). The most common technologies reviewed were drugs (24%, n = 60), devices (19%, n = 48), and care processes (12%, n = 31). Mean report completion time was 70 days. Thirty reports (12%) informed computerized decision support interventions. More than half of reports (56%, n = 139) were completed in the last 4 fiscal years for 65 requestors. Of the 64 eligible participants, 46 responded (72%). Requestors were satisfied with the report (mean = 4.4), and agreed it was delivered promptly (mean = 4.4), answered the questions posed (mean = 4.3), and informed their final decision (mean = 4.1).ConclusionsThis is the first examination of evidence synthesis activities by a hospital EPC in the United States. Our findings suggest hospital EPCs can efficiently synthesize and disseminate evidence addressing a range of clinical topics for diverse stakeholders, and can influence local decision making.© 2015 Society of Hospital Medicine.

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