• Internal medicine · Jan 2022

    Case Reports

    Miller Fisher Syndrome Following Vaccination against SARS-CoV-2.

    • Makoto Yamakawa, Keiichi Nakahara, Toshihito Nakanishi, Toshiya Nomura, and Mitsuharu Ueda.
    • Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Japan.
    • Intern. Med. 2022 Jan 1; 61 (7): 1067-1069.

    AbstractAfter BNT162b2 messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination, a 30-year-old man developed bilateral lateral gaze palsy, diplopia, absent tendon reflexes, and ataxic gait. Serum anti-GQ1b and anti-GT1a immunoglobulin G (IgG) antibodies were strongly positive. Based on those findings, he was diagnosed with Miller Fisher syndrome (MFS). Intravenous immunoglobulin therapy was administered, and his symptoms fully recovered within approximately 3 months. To the best of our knowledge, this is the first report to describe the development of MFS after COVID-19 mRNA vaccination.

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