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- Cassandra L Formeck, Carlos L Manrique-Caballero, Hernando Gómez, and John A Kellum.
- Division of Nephrology, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Faculty Pavilion, 4th Floor, Pittsburgh, PA 15224, USA; Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
- Crit Care Clin. 2022 Apr 1; 38 (2): 317-347.
AbstractAcute kidney injury (AKI) is one of the most important complications of critical illness and a significant public health concern. AKI is commonly associated with sepsis, cardiac dysfunction, and exposure to nephrotoxic medication; however, less common causes of AKI can lead to devastating patient outcomes when the underlying diagnosis is missed or delayed. These uncommon causes of AKI fall into 3 large categories: structural, immune mediated, and microvascular, including various types of thrombotic microangiopathy. Kidney imaging, urine studies, and serum hemolytic studies should be a routine part of the evaluation of AKI among critically ill patients.Copyright © 2021 Elsevier Inc. All rights reserved.
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