• Seok Hyun Kim, Soo Yong Lee, Ga Yun Kim, Ji Soo Oh, Jeongsu Kim, Kook Jin Chun, Min Ho Ju, Chee-Hoon Lee, Yeo-Jeong Song, and Joo-Young Na.
• Division of Cardiology, Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
• J. Korean Med. Sci. 2022 Apr 4; 37 (13): e104.

AbstractVaccines have become the mainstay of management against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) in the absence of effective antiviral therapy. Various adverse effects of COVID-19 vaccination have been reported, including cardiovascular complications such as myocarditis or pericarditis. Herein, we describe clinical records of a 63-year woman with fulminant myocarditis following ChAdOx1 nCoV-19 vaccination that was salvaged by heart transplantation. She complained chest pain, nausea, vomiting, and fever after the second vaccination. After the heart transplantation, the patient died due to necrotizing pneumonia on the 54th day of onset. Fulminant myocarditis is very rare after ChAdOx1 nCoV-19 vaccination but can be fatal.© 2022 The Korean Academy of Medical Sciences.

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