• N. Engl. J. Med. · Apr 2022

    Implanted System for Orthostatic Hypotension in Multiple-System Atrophy.

    • Jordan W Squair, Maxime Berney, Mayte Castro Jimenez, Nicolas Hankov, Robin Demesmaeker, Suje Amir, Aurelie Paley, Sergio Hernandez-Charpak, Gregory Dumont, Leonie Asboth, Gilles Allenbach, Fabio Becce, Patrick Schoettker, Gregoire Wuerzner, Julien F Bally, Grégoire Courtine, and Jocelyne Bloch.
    • From the Center for Neuroprosthetics and the Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL) (J.W.S., N.H., R.D., S.A., A.P., S.H.-C., G.D., L.A., G.C., J.B.), the Department of Clinical Neuroscience (J.W.S., N.H., R.D., S.A., A.P., S.H.-C., G.D., L.A., G.C., J.B.), the Service of Neurosurgery (J.W.S., G.C., J.B.), the Service of Nephrology and Hypertension (M.B., G.W.), the Service of Neurology (M.C.J., J.F.B.), the Department of Diagnostic and Interventional Radiology (F.B.), and the Service of Anesthesiology (P.S.), Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Defitech Center for Interventional Neurotherapies (NeuroRestore), EPFL-CHUV-UNIL (J.W.S., M.B., N.H., R.D., S.A., A.P., S.H.-C., G.D., L.A., G.C., J.B.), and the Department of Nuclear Medicine and Molecular Imaging, CHUV (G.A.) - all in Lausanne, Switzerland.
    • N. Engl. J. Med. 2022 Apr 7; 386 (14): 1339-1344.

    AbstractOrthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods. We implanted a system to restore regulation of blood pressure and enable a patient with multiple-system atrophy to stand and walk after having lost these abilities because of orthostatic hypotension. This system involved epidural electrical stimulation delivered over the thoracic spinal cord with accelerometers that detected changes in body position. (Funded by the Defitech Foundation.).Copyright © 2022 Massachusetts Medical Society.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…