• Curr Med Res Opin · Apr 2017

    Review

    Insulin glargine 300 units/mL: a guide for healthcare professionals involved in the management of diabetes.

    • Jodi Strong, Davida Kruger, and Lucia Novak.
    • a Ministry Medical Group , Stevens Point , WI , USA.
    • Curr Med Res Opin. 2017 Apr 1; 33 (4): 785-793.

    AbstractInsulin glargine 300 units/mL: Insulin glargine 300 units/mL (Gla-300) is a formulation of insulin glargine that delivers the same number of insulin units in one-third of the injectable volume of insulin glargine 100 units/mL (Gla-100). Glucose control: Recently approved in the United States and in Europe for use in type 1 and type 2 diabetes, Gla-300 has a more constant and evenly distributed glucose-lowering effect compared with Gla-100, with a duration of action beyond 24 hours and lower within-day and between-day intra-individual variability in blood glucose levels. These benefits translate into predictable and sustained glucose control from a once-daily injection, with potential for fewer hypoglycemia episodes and less weight gain.

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