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Review Case Reports
Acquired pure red cell aplasia in a patient with ankylosing spondylitis- a case report and literature review.
- Xianfang Shao, Wei Wei, Yangzhi Zhao, Xinyue Liang, and Qiuju Liu.
- Hematology Section, Cancer Center.
- Medicine (Baltimore). 2019 Jul 1; 98 (27): e16160.
RationaleAcquired pure red cell aplasia (PRCA) can be a secondary response to some autoimmune disorders. However, there is no data about the possibility of acquired PRCA being a secondary complication to ankylosing spondylitis (AS).Patient ConcernsA 42-year-old male who had a history of AS for 14 years. He got serious anemia 17 months ago. Bone marrow smear indicated PRCA.DiagnoseHe was diagnosed with acquired PRCA secondary to AS.InterventionThe combination treatment of immunosuppressants with hematopoiesis stimuli was successful.OutcomesThe patient recovered from PRCA, and showed improvement in his AS.LessonsAcquired PRCA can be secondary to AS. Cyclosporine is effective in controlling AS arthritis syndrome and in addition to immunosuppressants, promotion of erythroid hematopoiesis is equally important.
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