• Yan Liu, Qiang Lu, Xiao-Li Wu, Guo-Ju Shen, and Tao Luo.
• Department of Ultrasound, West China Hospital, Sichuan University, Chengdu.
• Medicine (Baltimore). 2019 Jul 1; 98 (28): e16425.

RationaleCalcifying fibrous tumor (CFT) is a rare benign mesenchymal tumor characterized by cytologically benign fibroblasts that produce abundant collagen with scattered lymphocytes, plasma cells, and psammomatous or dystrophic calcifications.Patient ConcernsA 37 years old women was initially diagnosed thyroid nodule in local hospital. She was referred to receive microwave ablation of the nodule in our hospital. The patient was in good health with occasional foreign body sensation in the neck. Routine laboratory examination was normal.DiagnosisThe lesion was suspected benign and originating from the esophagus rather than the thyroid gland by conventional ultrasound and contrast-enhanced ultrasound in our hospital and was finally proved to be CFT by pathology.InterventionsThe lesion was surgically removed.OutcomesThe patient recovered well and was followed up for 2 years without recurrence.LessonsAlthough imaging diagnosis of CFT is difficult, the findings of clear border, coarse calcification on conventional ultrasound and peripheral hypoenhancement without central enhancement on contrast-enhanced ultrasound (CEUS), together with real-time evaluation of the relationship between the tumor and esophagus help to distinguish CFT of cervical esophagus from other lesions in the neck.

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