• Lu Junfeng, Ma Lina, and Chen Xinyue.
• International Medical Department, Beijing Youan Hospital, Capital Medical University, Beijing, China.
• Medicine (Baltimore). 2019 Jul 1; 98 (29): e16222.

RationaleHIV-related lymphoma, especially non-Hodgkin lymphoma, is one of the most common malignant tumors in HIV/acquired immune deficiency syndrome (AIDS) patients. Autologous hematopoietic stem cell transplantation (AHSCT) for the patients with Burkitt lymphoma (BL) is needed to be further explored.Patient ConcernsA 57-year-old man was hospitalized with intermittent pain on upper abdomen and melena for >1 month.DiagnosisHIV antibody testing was positive. The upper gastrointestinal endoscopy was performed and histopathology and immunohistochemistry revealed BL.InterventionsHighly effective antiretroviral therapy and sixth cycles of chemotherapy were administered, followed by autologous hematopoietic stem cell transplantation.OutcomesThe patient has had tumor-free survival for >6 years with normal CD4+ T cell counts and HIV viral load below the lowest detection LESSONS:: The patient was treated with AHSCT followed complete remission after chemotherapy and achieved long-term disease-free survival. AHSCT may be a promising way for clinical cure of HIV-related BL.

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