• Miguel Ángel Serrano-Berrones and Sergio Baltazar Barragán-Padilla.
• Dirección Normativa de Supervisión y Calidad. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México.
• Gac Med Mex. 2019 Jan 1; 155 (Suppl 1): S27-S31.

BackgroundPreeclampsia occurs in 8% of pregnancies and generates 25% of perinatal deaths. Although its etiology is multifactorial, some metabolic alterations are associated with the endothelial dysfunction present in the disease, and its study could identify early markers of damage.ObjectiveTo determine the relationship between plasma concentration of triglycerides in pregnant patients with hypertensive disease induced by pregnancy.MethodsProspective study that included 147 healthy pregnant women and 120 women with hypertensive disease induced by pregnancy. Total cholesterol, low-density lipoprotein, high-density lipoprotein, Hemoglobin A1c, triglycerides, BH, QS, serum electrolytes, serum nitrites and liver function tests were determined.ResultsA significant difference was found in the concentration of triglycerides between normotensive and patients with preeclampsia (261.22 ± 80.27 vs. 361.46 ± 135.17 mg/dl, p < 0.0008). In addition, a lower serum concentration of nitrites was observed in patients with preeclampsia, which helps explain vasoconstriction.ConclusionsWe found an association between hypertriglyceridemia and the presence of diabetes mellitus II with the development of hypertensive disease induced by pregnancy.Copyright: © 2019 SecretarÍa de Salud.

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