• Gac Med Mex · Jan 2019

    Comparative Study

    Desempeño de las ecuaciones para estimar la tasa de filtración glomerular en pacientes mexicanos receptores de trasplante renal.

    • Jaime Antonio Borjas-García, Everardo Lugo-Vega, Lilia María de Guadalupe Llamazares-Azuara, and Marco Ulises Martínez-Martínez.
    • Hospital Central "Dr. Ignacio Morones Prieto", Departamento de Nefrología, San Luis Potosí, San Luis Potosí, México.
    • Gac Med Mex. 2019 Jan 1; 155 (3): 223-228.

    IntroductionThe management of kidney transplant recipients requires glomerular filtration rate (GFR) monitoring, which is an indicator of graft primary function and patient survival.ObjectiveTo evaluate the performance of different creatinine or cystatin-based formulas in the estimation of glomerular filtration rate in Mexican patients receiving kidney transplantation.Method30 transplant recipients were included, in whom the glomerular filtration rate was measured by means of iothalamate, and was also calculated using seven equations based on cystatin or creatinine.ResultsThe formula with the best performance was the one proposed by the chronic kidney disease epidemiology collaboration (CKD-EPI), with a bias of -2.4 mL/min/1.73 m2 and an accuracy of 9.6; 96.7 % of patients were within 30 % of the measured GFR. The second best formula was the modification of diet in renal disease (MDRD) equation. Cystatin-based equations showed a poor performance.ConclusionsOur study suggests that, in Mexican patients receiving kidney transplantations, the best equations to estimate GFR are the CKD-EPI and MDRD equations.Copyright: © 2019 SecretarÍa de Salud.

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