• Laura Conde-Ferráez, Ana Lilia Ceh-Guerrero, José Reyes Canché-Pech, Guadalupe Ayora-Talavera, and María Del Refugio González-Losa.
• Universidad Autónoma de Yucatán, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Unidad Biomédica, Yucatán, México.
• Gac Med Mex. 2019 Jan 1; 155 (4): 336-342.

IntroductionHuman cytomegalovirus (HCMV) is recognized as the most common cause of congenital viral infection, which can occur as a result of primary infection, reinfection or infection reactivation in the pregnant woman and be the cause of delay in neuronal development and sensorineural hearing loss in the neonate.ObjectiveTo identify CMVH infection in newborns by real-time polymerase chain reaction (RT-PCR) and cell culture.MethodObservational, cross-sectional, retrospective study with oral swab samples from 362 neonates born within a 10-month period in a public hospital of Mérida, Yucatán. RT-PCR was carried out for the detection of HCMV. Fibroblast primary cell culture was obtained from human foreskin tissue to isolate the virus. Only positive cases were followed.ResultsA prevalence of HCMV infection of 0.86 % was found by RT-PCR. No virus was isolated with cell culture. In the follow-up visits, sensory health and neurodevelopment were adequate.ConclusionThe prevalence of HCMV infection is similar to that of worldwide reports, and only was detected by RT-PCR. Asymptomatic infection detected 12-14 h after birth had no long-term health consequences.Copyright: © 2019 Permanyer.

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