• Resuscitation · Jun 2022

    Review

    Out-of-hospital Cardiac Arrest with Onset Witnessed by Emergency Medical Services: Implications for Improvement in Overall Survival.

    • Lauri Holmström, Kyndaron Reinier, Lorrel Toft, Henry Halperin, Angelo Salvucci, Jonathan Jui, and Sumeet S Chugh.
    • Center for Cardiac Arrest Prevention, Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, United States; Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.
    • Resuscitation. 2022 Jun 1; 175: 192719-27.

    AbstractOut-of-hospital cardiac arrest (OHCA) remains a major public health problem. Even in high-income countries, survival rates have plateaued in the range of ten percent, stimulating an ongoing interest in developing novel approaches to resuscitation. Emergency Medical Services (EMS)-witnessed OHCAs constitute a subgroup of overall OHCA that occur after the arrival of EMS, leading to rapid initiation of resuscitation and significantly improved survival. In this narrative review we summarize and interpret recent developments in knowledge of EMS-witnessed OHCA regarding prevalence, demographics, location, circumstances, survival outcomes and clinical profile. We examine the possibility of informing novel resuscitation approaches and enhancing mechanistic knowledge by studying EMS-witnessed OHCA, with the goal of improving overall survival from OHCA.Copyright © 2022 Elsevier B.V. All rights reserved.

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