• J Travel Med · Mar 2014

    Review

    LeishMan recommendations for treatment of cutaneous and mucosal leishmaniasis in travelers, 2014.

    • Johannes Blum, Pierre Buffet, Leo Visser, Gundel Harms, Mark S Bailey, Eric Caumes, Jan Clerinx, van ThielPieter P A MPP, Gloria Morizot, Christoph Hatz, Thomas P C Dorlo, and Diana N J Lockwood.
    • J Travel Med. 2014 Mar 1; 21 (2): 116-29.

    BackgroundTreatment of cutaneous leishmaniasis (CL) and mucosal leishmaniasis (ML) in travelers is still controversial. Over the last decade, national and international consortia have published recommendations for treating CL in travelers. These guidelines harmonize many issues, but there are some discrepancies.MethodsLeishmania parasites causing CL can now be genotyped by polymerase chain reaction techniques for detecting Leishmania DNA. Therefore, treatment recommendations can now be species based rather than based on geographical exposure. To review the evidence on which the recommendations were based, "LeishMan" (Leishmaniasis Management), a group of experts from 13 institutions in eight European countries, performed a PubMed MEDLINE) literature search and considered unpublished evidence and the experts' own personal experiences. The Oxford evidence grading system was used to evaluate the information.Results And ConclusionIn this article, the authors provide practical treatment recommendations for imported CL and ML in Europe, drawn up from the review by the European experts.

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