• A&A practice · Apr 2022

    Case Reports

    Central Neurogenic Hyperventilation and Hyperlactatemia After Resection of a Fourth Ventricle Tumor: A Case Report.

    • Gabriel Paquin-Lanthier, Kyle Rogan, Glenn McGuire, Tumul Chowdhury, and Lashmi Venkatraghavan.
    • From the Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
    • A A Pract. 2022 Apr 12; 16 (4): e01585.

    AbstractWe report a rare case of central neurogenic hyperventilation (CNH) and hyperlactatemia after resection of a fourth ventricle tumor. Our management consisted of close monitoring and exclusion of alternate causes of hyperventilation and hyperlactatemia. We hypothesize that a localized increase in tissue lactate, related to tumor metabolism, may have triggered CNH in our patient through stimulation of the brainstem respiratory centers. CNH should be considered during the differential diagnosis of perioperative hyperventilation with respiratory alkalosis in patients with posterior fossa tumors. Hyperlactatemia can trigger compensatory hyperventilation but will not result in alkalosis.Copyright © 2022 International Anesthesia Research Society.

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