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Dtsch. Med. Wochenschr. · Apr 2022
[Autoimmune Hepatitis - What is important for clinical practice?]
- Laura Vogelbacher, Robert Thimme, and Tobias Böttler.
- Dtsch. Med. Wochenschr. 2022 Apr 1; 147 (8): 470-480.
AbstractAutoimmune hepatitis is a rare but chronic autoimmune-mediated liver disease. Key features are elevated transaminases, hypergammaglobulinemia, presence of specific autoantibodies and typical histological features. Diagnostic scores are helpful in establishing the diagnosis. Immunosuppressive therapy should be initiated in every patient with inflammatory activity. First-line therapy includes steroids and azathioprine and results in biochemical and histological remission in the majority of patients. In most cases, lifelong therapy is required. Every patient should receive regular follow-up surveillance including biochemical parameters as well as sonography and elastography.Thieme. All rights reserved.
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