• Dtsch. Med. Wochenschr. · Mar 1999

    Case Reports

    [Recurrent subacute encephalopathy in the framework of idiopathic hypereosinophilic syndrome].

    • B Balestra, P Pedrazzi, and F Regli.
    • Medizinische Abteilung, Ospedale della Beata Vergine, Mendrisio.
    • Dtsch. Med. Wochenschr. 1999 Mar 19; 124 (11): 321-4.

    HistoryAn 81-year-old man, previously good health, suddenly developed confusion and rapidly progressive severe tetraparesis.InvestigationsPeripheral blood and bone marrow revealed marked eosinophilia: allergic, parasitic, neoplastic or vasculitic causes were excluded. Magnetic resonance imaging demonstrated multiple lesions in the cortical and subcortical white matter.Diagnosis, Treatment And CourseThe findings indicated idiopathic hypereosinophilic syndrome involving the central nervous system and treatment with high doses of glucocorticoids was started. After a stormy course almost complete recovery occurred.ConclusionIdiopathic hypereosinophilic syndrome can rarely manifest itself a an isolated severe subacute encephalopathy.

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