• Xin Liu, Yingni Luan, Lin Zhang, and Yanli Li.
• Department of Operating Room, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
• Medicine (Baltimore). 2022 Apr 1; 101 (13): e29122e29122.

BackgroundThere are no evidence-based data to confirm the efficacy of aromatic essential oil nursing in patients after laparoscopic cholecystectomy (LC). Therefore, in order to provide new evidence-based medical evidence for clinical treatment, we undertook this protocol for systematic review and meta-analysis to assess the effectiveness and safety of aromatic essential oil nursing on mental state of patients undergoing LC.MethodsThe retrieval strategy will be developed by the evidence-based medicine librarians for the US Library of Medicine database, the Cochrane Database of Systematic Reviews, and the Excerpta Medica database. The databases will be searched between June 2022 and July 2022. Studies will be included according to the following criteria: study population undergoing LC; group with aromatic essential oil nursing compared to a control group; outcome measures including anxiety, salivary cortisol, alpha amylase, and patient satisfaction; randomized controlled trials. All data will be analyzed using R version 3.4.3 to calculate pooled standardized mean differences for outcomes. The Cochrane Collaboration's tool will be used to assess the risk of bias for each included article.ResultsThe results of this paper will fill a gap in the literature regarding this project.ConclusionWe assume that the aromatic essential oil nursing has a positive effect.Registration Number10.17605/OSF.IO/E5WC9.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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