• Gustavo Aroca-Martínez, Lil Avendaño-Echavez, Carlos Garcia, Daniela Ripoll, Daniela Dianda, Andrés Cadena-Bonfanti, and Carlos G Musso.
• Facultad de Ciencias de La Salud, Universidad Simón, Barranquilla, Colombia.
• Ir J Med Sci. 2023 Apr 1; 192 (2): 923927923-927.

IntroductionSARS-CoV-2 infection can affect other organs aside from those of respiratory system, particularly the kidney, heart, blood, digestive tract, and nervous system. COVID-19 renal compromise consists of different syndromes since proteinuria, hematuria, and acute kidney injury (AKI), until chronic kidney disease. Since COVID-19-induced renal tubular damage has been described as a potential antecedent condition to AKI installation, it was decided to evaluate how COVID-19 affects tubular function.Materials And MethodSerum inflammatory parameters, urinalysis, and classical urinary indexes in COVID-19 admitted patients who had neither AKI nor chronic kidney disease (CKD) were evaluated. Statistical analysis was performed by applying Student t test.ResultsRenal tubular function was evaluated in 41 COVID-19 admitted patients who had neither AKI nor CKD. Patients' mean age was 56 years, males (79%), and with normal creatininemia (0.8 ± 0.2 mg/dL) and eGFR (105.7 ± 6.5 mL/min) values. It was found mild hypocalcemia and a relative increased fractional excretion (FE) of sodium, FE of calcium, FE of phosphorus, calcium-creatinine index, urinary osmolarity, and relative alkaline urine pH values.ConclusionTubular dysfunction was documented in COVID-19 patients.© 2022. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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