• Emily S Tonorezos, Richard J Cohn, Adam W Glaser, Jeremy Lewin, Eileen Poon, Claire E Wakefield, and Kevin C Oeffinger.
• Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA. Electronic address: emily.tonorezos@nih.gov.
• Lancet. 2022 Apr 16; 399 (10334): 156115721561-1572.

AbstractWorldwide advances in treatment and supportive care for children and adolescents with cancer have resulted in a increasing population of survivors growing into adulthood. Yet, this population is at very high risk of late occurring health problems, including significant morbidity and early mortality. Unique barriers to high-quality care for this group include knowledge gaps among both providers and survivors as well as fragmented health-care delivery during the transition from paediatric to adult care settings. Survivors of childhood and adolescent cancer are at risk for a range of late-occuring side-effects from treatment, including cardiac, endocrine, pulmonary, fertility, renal, psychological, cognitive, and socio-developmental impairments. Care coordination and transition to adult care are substantial challenges, but can be empowering for survivors and improve outcomes, and could be facilitated by clear, effective communication and support for self-management. Resources for adult clinical care teams and primary care providers include late-effects surveillance guidelines and web-based support services.Copyright © 2022 Elsevier Ltd. All rights reserved.

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