• Paediatric anaesthesia · Apr 2023

    Ketamine-Dexmedetomidine combination (KETODEX) for sedation in pediatric major surgery in a low-income country.

    • Sofia Vila Moutinho Tavares, João C Tavares, Borges MarquesJoanaJDepartment of Anesthesiology, Hospital de Braga, Braga, Portugal., Joana Teixeira de Figueiredo, and Passos de SouzaRenato LucasRLDepartment of Anesthesiology, Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, HCFMRP-USP, Ribeirão Preto, Brazil..
    • Department of Anesthesiology 1, Centro Hospitalar Universitário do Algarve, Faro, Portugal.
    • Paediatr Anaesth. 2023 Apr 1; 33 (4): 278281278-281.

    AbstractAnorectal malformations are one of the most frequent congenital malformations treated by pediatric surgeons. In low-income countries, the surgical and anesthetic management of children in need of these procedures can be challenging. Limited oxygen supply, lack of equipment, especially pediatric, and intensive care units make the use of regional anesthesia appealing. We present a series of four cases of anorectal malformations corrections in Guinea Bissau, in children up to 13 months of age, under regional anesthesia and sedation with ketodex, a mixture of ketamine and dexmedetomidine (in a proportion of 1 mg to 1 μg). No child developed respiratory depression requiring airway intervention or supplemental oxygen, or had hemodynamic instability.© 2022 John Wiley & Sons Ltd.

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