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- Nodoka Sekiguchi, Satoru Joshita, Toshikazu Yoshida, Masahiro Kurozumi, Kenji Sano, Michitaka Nakagawa, Tetsuya Ito, Tsuyoshi Matsushita, Daisuke Komatsu, Michiharu Komatsu, Toshiro Ito, Takeji Umemura, Shu-ichi Ikeda, Masumi Kadoya, Fumihiro Ishida, and Eiji Tanaka.
- Department of Medicine, Shinshu University School of Medicine, Japan.
- Intern. Med. 2013 Jan 1; 52 (17): 1903-8.
AbstractA 72-year-old man suffered from paraparesis with a sensory impairment and bladder and rectal disturbances. Magnetic resonance imaging T2-weighted images depicted a high-intensity lesion in the spinal cord that was consistent with myelitis. A blood examination revealed severe thrombocytopenia and liver dysfunction. No malignant cells were detected by peripheral smears or bone marrow biopsy. Systemic computed tomography detected hepatosplenomegaly and ascites but no lymphadenopathies. Transjugular liver biopsy (TJLB) safely confirmed a diagnosis of intravascular large B-cell lymphoma (IVLBCL), and the patient achieved a complete response following treatment with an appropriate chemotherapy. TJLB is therefore a timely and accurate diagnostic approach for IVLBCL, especially when a bleeding tendency and ascites are noted.
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