• Fei Yao, Xutao Wu, Huacheng Zhao, and Chun Gan.
• Department of Gastroenterology, the Second Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Jiangxi, China.
• Medicine (Baltimore). 2022 Mar 11; 101 (10): e29033e29033.

BackgroundGuidelines for the management of irritable bowel syndrome (IBS) recommend that psychological therapies should be considered, but their relative efficacy is unknown. We performed a protocol for systematic review and meta-analysis to try to resolve this uncertainty.MethodsTwo individual researchers conducted the platform searches on Ovid Medline In-Process & Other Non-Indexed Citations, Ovid MEDLINE, Ovid EMBASE, Ovid PsycINFO, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus from inception to February 2022. Systematic review and meta-analysis of the data will be performed in STATA13.0 software according to the preferred reporting items for systematic reviews and meta-analyses protocols guidelines. Two authors independently performed the literature searching, data extraction, and quality evaluation. Risk of bias was assessed using the Cochrane Risk of Bias Tool for randomized controlled trials.ResultsA synthesis of current evidence of psychological interventions for IBS will be provided in this study.ConclusionThis result will provide a comprehensive analysis and synthesis to inform practitioners and policy makers about the effectiveness of psychological interventions for patients with IBS.Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

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