• Cansu Dogan, Atakan Yilmaz, Mert Ozen, Murat Seyit, Alten Oskay, Aykut Kemanci, Mehmet Uluturk, and Ibrahim Turkcuer.
• Pamukkale University, Faculty of Medicine, Department of Emergency Medicine, 20070, Denizli, Turkey.
• Am J Emerg Med. 2022 Jun 1; 56: 223-227.

IntroductionNon-traumatic back pain constitutes roughly 5% of the admissions to emergency departments. This study seeks to compare the efficacy of intravenously administered paracetamol, dexketoprofen, and ibuprofen in patients with non-traumatic acute low back pain.MethodsThis study was designed as a randomized, double-blinded investigation and carried out at a tertiary hospital. 210 eligible patients without trauma who presented with low back pain were recruited for the study and randomized into paracetamol (n = 71), dexketoprofen (n = 70), and ibuprofen (n = 69) groups. The measurements at 0, 15, 30 and 60 min were noted down by using a 100 mm VAS, and the relevant comparisons were made.ResultsThe VAS scores at 0 and 60 min in the paracetamol, dexketoprofen, and ibuprofen groups decreased on average by 40 mm, 42 mm, and 43 mm, respectively. The baseline and final pain scores of each drug group differed significantly (p < 0.05), though the between-group analysis revealed no significant difference (p > 0.05).ConclusionGiven the obtained data, we did not note a significant difference between intravenous paracetamol, dexketoprofen and ibuprofen with respect to pain efficacy in non-traumatic acute low back pain. Based on the patients' clinical conditions and histories, we concluded that the choice of medication might not change the efficacy of the treatment and patient comfort.Copyright © 2022 Elsevier Inc. All rights reserved.

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