• Am. J. Clin. Pathol. · Mar 1990

    Comparative Study

    Rapid differentiation of subarachnoid hemorrhage from traumatic lumbar puncture using the D-dimer assay.

    • D T Lang, L B Berberian, S Lee, and M Ault.
    • Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048.
    • Am. J. Clin. Pathol. 1990 Mar 1;93(3):403-5.

    AbstractThe D-dimer assay of 40 cerebral spinal fluid (CSF) samples accurately differentiated subarachnoid hemorrhage (SAH) from traumatic lumbar puncture. The D-dimer assay was positive in all six patients with subarachnoid hemorrhage. Negative D-dimer values were obtained in control groups of 14 patients with hemorrhagic CSF secondary to traumatic lumbar puncture (LP) and in 20 patients with normal CSF. The D-dimer assay proved to be a better test than xanthochromia or the decline in erythrocyte count in sequentially collected tubes in differentiating subarachnoid hemorrhage from traumatic LP.

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