• Eva Tseng, Nowella Durkin, Jeanne M Clark, Nisa M Maruthur, Jill A Marsteller, and Jodi B Segal.
• Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. etseng3@jhmi.edu.
• J Gen Intern Med. 2022 Dec 1; 37 (16): 411241194112-4119.

BackgroundThe incidence of diabetes in the general US population (6.7 per 1000 adults in 2018) has not changed significantly since 2000, suggesting that individuals with prediabetes are not connecting to evidence-based interventions.ObjectiveWe sought to describe the clinical care of individuals with prediabetes, determine patient factors associated with this care, and evaluate risk for diabetes development.DesignRetrospective cohort study using linked claims and electronic health record data.ParticipantsWe created a cohort of adults with prediabetes based on laboratory measures. We excluded patients with a prior history of diabetes, pregnancy in prior 6 months, or recent steroid use.Main MeasuresWe measured ordering and completion of clinical services targeting prediabetes management and diabetes incidence within 12 months following cohort entry. We tested the strength of the association between individuals' characteristics and outcomes of interest using bivariate and multiple logistic regression.ResultsOur cohort included 3888 patients with a laboratory diagnosis of prediabetes (incident or prevalent prediabetes). Within 12 months, 63.4% had repeat glycemic testing, yet only 10.4% had coded diagnoses of prediabetes, 1.0% were referred for nutrition services, and 5.4% were prescribed metformin. Most patients completed labs and nutrition visits when referred and filled metformin when prescribed. Individuals with a higher glycemic level or BMI were more likely to receive prediabetes clinical care. Six percent of individuals developed diabetes within 12 months of cohort entry and had higher glycemic levels and BMI ≥ 30 kg/m2. In the adjusted model, Black individuals had 1.4 times higher odds of developing diabetes than White individuals.ConclusionsRates of prediabetes clinical care activities are low and have not improved. Strategies are urgently needed to improve prediabetes care delivery thereby preventing or delaying incident diabetes.© 2022. The Author(s) under exclusive licence to Society of General Internal Medicine.

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